Completed Research Studies
Dr. Alan Thorson
- The Neuromuscular Stimulation System for Dynamic Anal Myoplasty. November 1994-April 2000. Medtronic, Inc. Investigator.
- Role of Peri-Strips as a Buttress in Intestinal Anasotmosis. March 1996-December 1997. Bio-Vascular, Inc. Principal Investigator.
- The Importance of EGF Receptors in the Growth of Anal Squamous Cell Carcinoma. August 1997-June 1999. Creighton University Health Futures Foundation. Co-Investigator.
- A Phase III Prospective Randomized Trial Comparing Laparoscopic Assisted Colectomy Versus Open Colectomy for Colon Cancer. May 1998-October 2001. National Cancer Institute Grant CA25224 to the North Central Cancer Treatment Group. Institutional Principal Investigator.
- Closure of Loop Ileostomy: Decreasing the Length of the Operation with the Use of a Sodium Hyaluronate Based Bioresorbable Solution. June 1998-February 2001. Genzyme Corporation. Investigator.
- A Trial to Evaluate the Long-Term Tolerability, Safety, Subject Satisfaction, Pharmacokinetics and Use Patterns of Oral R108512 Tablets In Subjects With Chronic Constipation. July 1998-April 2001. Janssen Research Foundation. Investigator.
- Arachidonic Acid Metabolism in Human Colon Cancer. February 1999-April 2001. Section of Colon and Rectal Surgery, Creighton University. Co-investigator.
- Arachidonic Acid Metabolism in Inflammatory Bowel Disease. February 1999-April 2001. Section of Colon and Rectal Surgery, Creighton University. Co-investigator.
- Acticon® Neo-Sphincter Clinical Assessment. October 1999-April 2003. American Medical Systems. Investigator.
- A Phase II Study of Local Excision Alone or Local Excision Plus Adjuvant Chemoradiation Therapy for Small Distal Rectal Cancers. December, 2001- January, 2003. Cancer and Lymphoma Group B. Investigator.
- The Basis of Improved Prognosis in Human Colorectal Cancer Demonstrating High Microsatellite Instability. March 2000-February 2001. Section of Colon and Rectal Surgery, Creighton University. Co-Investigator.
- A Randomized Prospective, Multi-Centered Parallel Group Study Comparing the Traditional Surgical Treatment of Hemorrhoidal Disease to Stapled Hemorrhoidectomy Using the Circular Stapler. May 2001-December 2003. Ethicon Endo-Surgery, Inc. Investigator.
- A Prospective Study of the Prognostic Significance of Micro Satellite Instability in Patients with early Age-of-Onset Colorectal Cancer. January 2004-December 2004. American College of Surgeons Oncology Group. Investigator.
- Timing of Rectal Cancer Response to Chemoradiation. February 2004-current. National Institutes of Health #03451. Institutional Principal Investigator.
- Peri-Strips® with PSD Veritas® Collagen Matrix Staple Line Protection for Colorectal Surgical Procedures Post Marking. August 2005-current. Synovis Surgical Innovations. Investigator.
- An Open Multicenter Study to Evaluate the Efficacy and Safety of the NASHA/Dx For the Treatment of Fecal Incontinence. March 2006-current. Q-Med Corporation. Investigator.
Dr. Charles Ternent
- A Phase III prospective, randomized trial comparing laparoscopic-assisted colectomy versus open colectomy for colon cancer. 1995-2001.
- Study of neuromuscular stimulation system for dynamic anal myoplasty. 1996-2000.
- PYY gut hormone levels and GI motility following restorative proctocolectomy for refractory chronic ulcerative colitis. Thomas Adrian, PhD., Creighton University School of Medicine, Omaha, Nebraska, 1996-2000.
- Lipoxygenase and cyclooxygenase induced inhibition of colorectal cancer cell growth. Creighton University, Omaha, Nebraska, Thomas Adrian PhD., 1996-2000.
- Evaluation of the efficacy, the safety and the tolerability of XXX (enterokinetic) given subcutaneously in patients undergoing elective partial colectomies. 1997-1998.
- A double-blind, placebo-controlled trial to evaluate the efficacy and safety of XXX tablets in subjects with chronic constipation. 1998-1999.
- Arachidonic Acid Metabolism in Human Colon Cancer and in Inflammatory Bowel Disease. 1998-2001.
- Closure of Loop Ileostomy: Decreasing the Length of the Operation with Use of a Sodium Hyaluronate-based Bioresorbable Membrane. 1998-2001.
- A Trial to Evaluate the Long-Term Tolerability, Safety, Subject Satisfaction, Pharmacokinetics, and Use Patterns of Oral XXX Tablets in Subjects with Chronic Constipation. 1998-2001.
- A two-period, double-blind, placebo-controlled trial to evaluate the effects of re-treatment of XXX on efficacy and safety in subjects with chronic constipation. 1999-2000.
- A Randomized, Prospective, Multicentered, Parallel Group Study Comparing the Ferguson Closed Wound Surgical Treatment of Hemorrhoid Disease to Stapled Hemorrhoidectomy using the XXXXXX Circular Stapler. 2001-2004.
- A Phase II Study of Local Excision Alone or Local Excision plus Adjuvant Chemoradiation Therapy for Small, Distal Rectal Cancer.
- A Prospective Study of the Prognostic Significance of Microsatellite Instability in Patients with Early Age Onset of Colorectal Cancer. 2003-2005.
- A Phase III Prospective Randomized Trial Comparing Laparoscopic-Assisted Resection versus Open Resection for Rectal Cancer. 2008-2010.
- Timing of Rectal Cancer Response to Chemoradiation. 2003-present.
- Clinical outcomes in a prospective institutional database of colorectal cancer patients and associated perioperative morbidity-mortality, survival and return of bowel function issues. 2004-present.
- A Prospective, Multi-center, Randomized, Controlled, Third-Party Blinded Study of XXX to Prevent Parastomal Hernia Formation in Patients Undergoing Surgery for Permanent Abdominal Wall Ostomies. 2008-2012.
- Impact of Routine Ostomy Intubation in Patients Who Undergo Permanent or Temporary Ostomy Creation. 2009-2014
- Characterization of Outcome for Rare Colon and Rectal Tumors. 2010-2012.
- A Phase 2 Prospective Evaluation of Immunotherapy for Perianal HPV Condylomata. 2012-2014.
- Prospective Evaluation of Satisfaction and Quality of Life in Outpatient Anorectal Surgery. 2012-2015.
- A Phase 3b, Randomized, Double-Blind, Placebo-Controlled, Parallel-Treatment Group, Multicenter Efficacy and Safety Study of XXXX in Subjects with Anal Fissure. 2013.
- A Phase 3 Study of Efficacy and Safety of Topical XXX to Prevent Incisional Wound Infection in Colorectal Surgery Patients. 2014-2015.
Dr. Jennifer Beaty
- A Prospective, Multi-center, Randomized, Controlled, Third-Party Blinded Study of XXX to Prevent Parastomal Hernia Formation in Patients Undergoing Surgery for Permanent Abdominal Wall Ostomies. 2008-2012.
- Impact of Routine Ostomy Intubation in Patients Who Undergo Permanent or Temporary Ostomy Creation. 2009-2014
- Characterization of Outcome for Rare Colon and Rectal Tumors. 2010-2012.
- A Phase 2 Prospective Evaluation of Immunotherapy for Perianal HPV Condylomata. 2012-2014.
- Prospective Evaluation of Satisfaction and Quality of Life in Outpatient Anorectal Surgery. 2012-2015.
- A Phase 3b, Randomized, Double-Blind, Placebo-Controlled, Parallel-Treatment Group, Multicenter Efficacy and Safety Study of XXXX in Subjects with Anal Fissure. 2013.
- A Phase 3 Study of Efficacy and Safety of Topical XXX to Prevent Incisional Wound Infection in Colorectal Surgery Patients. 2014-2015.
Colon and Rectal Surgery Completed Research Activities
Colon and Rectal Surgery- Anal Fissure
- A Phase 3b, Randomized, Double-Blind, Placebo-Controlled, Parallel-Treatment Group, Multicenter Efficacy and Safety Study of XXXX in Subjects with Anal Fissure
Colon and Rectal Surgery- Anorectal Surgery
- Patient Satisfaction After Outpatient Anorectal Surgery
- The Neuromuscular Stimulation System for Dynamic Anal Myoplasty
- Acticon™ Neosphincter
Colon and Rectal Surgery- Colon, Rectal, and Anal Cancer
- Colon, Rectal, and Anal Cancer Database Study
- Timing of Rectal Cancer Response to Chemoradiation
- A Phase II Study of Local Excision Alone or Local Excision plus Adjuvant Chemoradiation Therapy for Small, Distal Rectal Cancer
- A Phase II Multicenter, Randomized Trial Evaluating 3-Year Disease Free Survival in Patients with Locally Advanced Rectal Cancer Treated with Chemoradiation Plus Induction or Consolidation Chemotherapy and Total Mesorectal Excision or Non-Operative Mangement
- A Prospective Study of the Prognostic Significance of Microsatellite Instability in Patients with Early Age Onset of Colorectal Cancer
- Characterization of Outcome for Rare Colon and Rectal Tumors
- A Phase III Prospective Randomized Trial Comparing Laparoscopic- Assisted Resection versus Open Resection for Rectal Cancer
- Arachidonic Acid Metabolism in Human Colon Cancer
- The Basis of Improved Prognosis in Human Colorectal Cancer Demonstrating High Microsatellite Instability
- Lipoxygenase and Cycloxygenase Induced Inhibition of Colorectal Cancer Cell Growth
Colon and Rectal Surgery- Condyloma
- Phase II Study of the Treatment of Perianal Condyloma Acuminata with Intralesional Immunotherapy Using Skin Test Antigens
Colon and Rectal Surgery- Constipation
- A Trial to Evaluate the Long-Term Tolerability, Safety, Subject Satisfaction, Pharmacokinetics, and Use Patterns of Oral XXX Tablets in Subjects with Chronic Constipation
- A two-period, double-blind, placebo-controlled trial to evaluate the effects of re-treatment of XXX on efficacy and safety in subjects with chronic constipation.
- A double-blind, placebo-controlled trial to evaluate the efficacy and safety of XXX tablets in subjects with chronic constipation
Colon and Rectal Surgery- Inflammatory Bowel Disease
- Arachidonic Acid Metabolism in Inflammatory Bowel Disease
Colon and Rectal Surgery- Hemorrhoids
- A Randomized, Prospective, Multicentered, Parallel Group Study Comparing the Ferguson Closed Wound Surgical Treatment of Hemorrhoid Disease to Stapled Hemorrhoidectomy using the XXXXXX Circular Stapler
Colon and Rectal Surgery- Ostomy Closure
- Closure of Loop Ileostomy: Decreasing the Length of the Operation with Use of a Sodium Hyaluronate-based Bioresorbable Membrane
Colon and Rectal Surgery- Ostomy Creation
- Impact of Routine Ostomy Intubation in Patients Who Undergo Permanent or Temporary Ostomy Creation
Colon and Rectal Surgery- Parastomal Hernia
- A Prospective, Multi-center, Randomized, Controlled, Third-Party Blinded Study of XXX to Prevent Parastomal Hernia Formation in Patients Undergoing Surgery for Permanent Abdominal Wall Ostomies
Colon and Rectal Surgery- Surgery
- Evaluation of the efficacy, the safety and the tolerability of XXX (enterokinetic) given subcutaneously in patients undergoing elective partial colectomies
Colon and Rectal Surgery- Surgical Wound Infections
- Phase 3 Study of Efficacy and Safety of Topical XXX to Prevent Incisional Infections among Colorectal Surgery Patients
Colon and Rectal Surgery- Ulcerative Colitis
- PYY Gut Hormone Levels and GI Motility Following Restorative Proctocolectomy for Refractory Chronic Ulcerative Colitis